Drug Name

Celebrex (Celecoxib)

Drug Uses

Celecoxib is familiar for the relief of pain, fever, prominence, and tenderness caused by osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. Celecoxib does not hinder the progression of either group of arthritis. It reduces not the symptoms and signs of arthritis. Celecoxib has been approved for patients with familial FAP who be suffering with not had their colons removed. Celebrex also is approved for the succour of acute pain and the grieve of menstrual cramps (noteworthy dysmenorrhea).

How to use

The lowest real dose should be tempered to for each patient. For the directorship of osteoarthritis, the dose in the main is 100 mg twice constantly or 200 mg as a single prescribe. For rheumatoid arthritis, the quantity usually is 100 or 200 mg twice day after day. For acute pain or menstrual cramps, the portion is 400 mg as a single portion on the first day, followed by an additional 200 mg if needed, then 200mg twice everyday as needed. For FAP, the recommended quantity is 400 mg twice routine.

Drug Class and Mechanism

Celecoxib is a nonsteroidal anti-frantic drug (NSAID) that is worn to treat arthritis, labour, menstrual cramps, and colonic polyps. Prostaglandins are chemicals that are urgent contributors to the inflammation of arthritis that causes the drag, fever, swelling and tenderness. Celecoxib blocks the enzyme that makes prostaglandins (cyclooxygenase 2), resulting in mark down concentrations of prostaglandins. As a consequence, infection and its accompanying pain, fever, excrescence and tenderness are reduced. Celecoxib differs from other NSAIDs in that it causes less sore and ulceration of the stomach and intestine (at least with sawn-off-term treatment) and does not interpose with the clotting of blood. NSAIDs make been found to forbid the formation and reduce the proportions of polyps in patients with the genetic disorder, familial adenomatous polyposis (FAP). In FAP, patients broaden large numbers of polyps in their colons, and the polyps invariably behove malignant. The only restore to health of FA

Missed Dose

Wolf the missed dose as before long as you remember. If it is almost dated for the next dose, omit the dose you missed and make oneself scarce only the next regularly scheduled dosage as directed. Do not take a duplicate dose of this medication unless your doctor directs in another situation.

Storage

Capsules should be stored at 25 degrees C (77 degrees F). It is okay for condensed periods in temperatures between 15-30 degrees C (59-86 degrees F).

Warnings/Precautions

There are no restrictions on viands, beverages, or activity while intriguing celecoxib unless way directed by your doctor. Concomitant use of celecoxib with aspirin or other NSAIDs (e.g., ibuprofen, naproxen, etc.) may extension the occurrence of stomach and intestinal ulcers. Fluconazole (Diflucan) increases the concentration of celecoxib in the council by inhibiting the breakdown of celecoxib in the liver. Accordingly, treatment with celecoxib should be initiated at the lowest recommended doses in patients who are engaging fluconazole. Celecoxib increases the concentration of lithium (Eskalith) in the blood by 17%. So, lithium therapy should be closely monitored during and after psychotherapy with celecoxib. Persons, engaging the anticoagulant (blood thinner) warfarin (Coumadin), should take their blood tested when initiating or changing celecoxib treatment, peculiarly in the first few days, for any changes in the effects of the anticoagulant. Persons, who drink more than 3 lush bevera

Possible Side Effects

Although pot-belly and intestinal ulcers turn up dawn on with the use of celecoxib, their amount is less than with other NSAIDs in runty-term studies. Celecoxib does not kibitz with the function of the blood platelets and, as a sequel, does not reduce clotting and conduct to increased bleeding like other NSAIDs. The most everyday adverse effects are pain in the arse, abdominal pain, dyspepsia, diarrhea, nausea, flatulence and insomnia. Other side effects list fainting, kidney default, heart failure, aggravation of hypertension, coffer pain, ringing in the ears, deafness, taste and intestinal ulcers, bleeding, blurred idea, anxiety, photosensitivity, value gain, water retention, flu-like symptoms, drowsiness and taste. Allergic reactions can turn up dawn on with celecoxib. Individuals who have on the agenda c trick developed allergic reactions (impetuous, itching, difficulty breathing) from sulfonamides (e.g., Bactrim), aspirin or other NSAIDs may encounter an allergic reaction to celecoxib and should not view as celecoxib.

More Information

Declare your doctor right away if you develop abdominal trouble, tenderness, or discomfort; nausea; bloody toss one's cookies; bloody, black, or rest stools; unexplained mass gain; swelling or damp retention; fatigue or drowsiness; a skin rash; itching; yellowing of the skin or eyes;\\"flu-like\\" symptoms; or bizarre bruising or bleeding. These symptoms could be old signs of dangerous side effects. If you know-how any of the following serious side effects, refrain from taking celecoxib and search for medical treatment or bid your doctor right now: an allergic reaction (snag breathing; closing of your throat; enlargement of your lips, gaffe, or face; or hives). Other, less momentous side effects may be more liable to occur. Continue to imbibe celecoxib and talk to your doctor if you savoir faire flatulence or diarrhea; dizziness; cephalalgia; or insomnia. Side effects, other than those listed here, may also come off. Talk to your doctor less any side effect that seems unconventional or that is especially bothersome.